Celltheon - Cell Line Development, Cell Therapies and Gene Technology

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  • HOME
  • ABOUT US
  • SERVICES
  • Products and Technology
  • NEWS & EVENTS
  • EMPLOYMENT
  • CONTACT

PRODUCTS & TECHNOLOGY

CELLTHEON SMART™ VECTORS

Using sophisticated bioinformatic tools, Celltheon has developed novel regulatory expression elements that allow for high expression of recombinant therapeutics from highly stable cell lines.
Using novel in-house-developed bioinformatics tools, Celltheon has generated over 100 vectors and tested each under an array of conditions and proteins of interest. The SMART™ vector panel goes beyond the one size fits all approach to expression while maintaining low costs and timelines due to prior screening efforts. Technological developments include enhanced selection power, enhanced promoters for transient and stable, and novel synergistic combinations of expression elements all of which add up to 3 week timelines for reproducible pool titers of greater than 2 g/L.

Key features of the Celltheon SMART™ Vectors:
  • Celltheon suPRE™ Elements
  • Novel promoter technologies
  • Optimized on multiple selection markers
  • >90% transfection efficiency
  • No need for gene amplification
  • >2 g/L titers at pool stage
  • Non-viral based vectors
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